trifluridine ophthalmic

Adult Dosing .

Dosage forms:  SOL: 1%

HSV keratoconjunctivitis, primary

[1 gtt in eye(s) q2h while awake until re-epithelization, then 1 gtt q4h while awake x7 days]

Max: 9 gtt/eye/day, 21 days/episode; Info: give at least 5 gtt/day after re-epithelization

HSV epithelial keratitis, recurrent

[1 gtt in eye(s) q2h while awake until re-epithelization, then 1 gtt q4h while awake x7 days]

Max: 9 gtt/eye/day, 21 days/episode; Info: give at least 5 gtt/day after re-epithelization

mpox, ocular (off-label)

[1 gtt in eye(s) q2h while awake x2 wk or until re-epithelization, then 1 gtt q4h while awake]

Max: 9 gtt/eye/day; 4wk; Info: give at least 5 gtt/day after re-epithelization; consider giving w/ tecovirimat

Peds Dosing .

Dosage forms:  SOL: 1%

HSV keratoconjunctivitis, primary

[6 yo and older]

Dose: 1 gtt in eye(s) q2h while awake until re-epithelization, then 1 gtt q4h while awake x7 days; Max: 9 gtt/eye/day, 21 days/episode; Info: give at least 5 gtt/day after re-epithelization

HSV epithelial keratitis, recurrent

[6 yo and older]

Dose: 1 gtt in eye(s) q2h while awake until re-epithelization, then 1 gtt q4h while awake x7 days; Max: 9 gtt/eye/day, 21 days/episode; Info: give at least 5 gtt/day after re-epithelization

mpox, ocular (off-label)

[1 gtt in eye(s) q2h while awake x2 wk or until re-epithelization, then 1 gtt q4h while awake]

Max: 9 gtt/eye/day; 4wk; Info: give at least 5 gtt/day after re-epithelization; consider giving w/ tecovirimat