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Brevital
methohexital
Black Box Warnings .
Appropriate Use
use only in hospital/ambulatory care setting w/ continuous resp./cardiac fxn monitoring, resuscitative drugs, appropriate ventilation/intubation equipment and personnel trained/skilled in airway management; continuously monitor deeply sedated pts by 1 designated person other than practitioner performing procedure
Adult Dosing .
Dosage forms: INJ
general anesthesia induction
- [50-120 mg IV x1]
- Alt: 1-1.5 mg/kg/dose IV x1
general anesthesia maintenance
- [20-40 mg IV q4-7min prn]
- Alt: 6 mg/min IV, titrate to effect
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [see below]
- mild-moderate impairment: not defined, caution advised; severe impairment: avoid use
Peds Dosing .
- Dosage forms: INJ
general anesthesia induction
- [>1 mo]
- Dose: 6.6-10 mg/kg/dose IM x1; Alt: 25 mg/kg/dose PR x1; Info: use injectable form for PR admin, see pkg insert for dilution instructions
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [see below]
- mild-moderate impairment: not defined, caution advised; severe impairment: avoid use