polyethylene glycol 3350

Adult Dosing .

Dosage forms:  PWDR: 17 g per capful, 17 g per pkt

constipation

[17 g PO qd]

Info: dissolve in 4-8 oz of liquid; may take 1-4 days to produce BM; use shortest effective tx duration

bowel prep (off-label)

[split-dose regimen]

Dose: 238 g PO in divided doses x2 days; Info: dissolve 238 g in 2 L clear liquid; drink 240 mL q10min x4 doses evening before procedure; on day of procedure approx. 5h before procedure, drink 240 mL q10min x4 doses

[day-before regimen]

Dose: 238 g PO in divided doses x1 day; Info: dissolve 238 g in 2 L clear liquid; drink 240 mL q10min until consumed on evening before procedure

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  PWDR: 17 g per capful, 17 g per pkt

bowel prep (off-label)

[<50 kg]

Dose: 4 g/kg/day PO divided q4-6h x1 day; Start: day before procedure; Max: 255 g/day; Alt: 2 g/kg/day PO divided q4-6h x2 days prior to procedure; Info: dissolve dose in 1.5 L of clear liquid

[>50 kg]

Dose: 238 g/day PO in divided doses x1 day; Start: day before procedure; Max: 255 g/day; Alt: 2 g/kg/day PO in divided doses x2 days prior to procedure; Info: dissolve dose in 1.5 L of clear liquid and give each dose over 2-4h

constipation, chronic (off-label)

[<20 kg]

Dose: 0.2-0.8 g/kg/dose PO qd; Start: 0.4 g/kg/dose PO qd; Max: 17 g/day; Info: dissolve in 4-8 oz of liquid; treat x2 mo minimum and x1 mo minimum after sx resolution; taper dose gradually to D/C

[>20 kg]

Dose: 17 g PO qd; Info: dissolve in 4-8 oz of liquid; may take 1-4 days to produce BM; use shortest effective tx duration

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]