Select a medication above to begin.
doxepin
generic
Black Box Warnings .
Suicidality
depression or anxiety use: incr. suicidality risk in children, adolescents, and young adults w/ major depressive or other psychiatric disorders; weigh risk vs. benefit; in short-term studies of antidepressants vs. placebo, suicidality risk not incr. in pts >24 yo, and risk decr. in pts 65 yo and older; depression and certain other psychiatric disorders themselves assoc. w/ incr. suicide risk; observe all pts for clinical worsening, suicidality, or unusual behavior changes; advise families and caregivers of need for close observation and communication w/ prescriber; not approved for peds use
Adult Dosing .
Dosage forms: CAP: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg; TAB: 3 mg, 6 mg; SOL: 10 mg per mL
insomnia
- [6 mg PO qhs]
- Max: 6 mg/day; Info: for sleep maintenance; give w/in 30min of bedtime; in elderly pts, start 3 mg PO qhs; avoid meals w/in 3h of admin; reassess if no response after 7-10 days
depression
- [150-300 mg PO qhs]
- Start: 25-75 mg PO qhs; Max: 300 mg/day; Info: reduce dose in elderly pts; may divide doses; taper dose gradually to D/C
anxiety
- [150-300 mg PO qhs]
- Start: 25-75 mg PO qhs; Max: 300 mg/day; Info: reduce dose in elderly pts; may divide doses; taper dose gradually to D/C
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [insomnia]
- hepatic impairment: start 3 mg qhs
- [depression or anxiety]
- hepatic impairment: not defined, caution advised
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.