Norditropin

Adult Dosing .

Dosage forms:  INJ (FlexPro pen): 5 mg per 1.5 mL, 10 mg per 1.5 mL, 15 mg per 1.5 mL, 30 mg per 3 mL

growth hormone deficiency

[non weight-based dosing]

Dose: individualize dose SC qd; Start: 0.15-0.3 mg SC qd, may incr. dose by 0.1-0.2 mg/day q1-2 months; Info: adjust dose based on IGF-1 levels and sx

[weight-based dosing]

Dose: individualize dose SC qd; Start: 0.004 mg/kg/dose SC qd; Max: 0.016 mg/kg/day; Info: not recommended for obese pts; adjust dose based on IGF-1 levels and sx

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (FlexPro pen): 5 mg per 1.5 mL, 10 mg per 1.5 mL, 15 mg per 1.5 mL, 30 mg per 3 mL

growth hormone deficiency

[0.024-0.034 mg/kg/dose SC 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

short stature, Noonan syndrome-assoc.

[up to 0.066 mg/kg/dose SC qd]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

short stature, Turner syndrome-assoc.

[up to 0.067 mg/kg/dose SC qd]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

short stature, SGA-assoc.

[up to 0.067 mg/kg/dose SC qd]

Start: 0.033-0.067 mg/kg/dose SC qd; Info: for pts w/ no catch-up growth by 2-4 yo; D/C when pt reaches satisfactory ht, epiphyses close, or no response

idiopathic short stature

[up to 0.067 mg/kg/dose SC qd]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

growth failure, Prader-Willi syndrome-assoc.

[up to 0.034 mg/kg/dose SC qd]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]