Genotropin

Adult Dosing .

Dosage forms:  INJ (cartridge): 5 mg per mL, 12 mg per mL; INJ (MiniQuick pre-filled syringe): 0.2 mg per 0.25 mL, 0.4 mg per 0.25 mL, 0.6 mg per 0.25 mL, 0.8 mg per 0.25 mL, 1 mg per 0.25 mL, 1.2 mg per 0.25 mL, 1.4 mg per 0.25 mL, 1.6 mg per 0.25 mL, 1.8 mg per 0.25 mL, 2 mg per 0.25

growth hormone deficiency

[0.04-0.08 mg/kg/wk SC divided 6-7x/wk]

Start: up to 0.04 mg/kg/wk SC divided 6-7x/wk, incr. dose q4-8wk; Max: 0.08 mg/kg/wk; Alt: start 0.15-0.3 mg SC qd, incr. 0.1-0.2 mg/day q1-2mo; Info: for childhood- or adult-onset growth hormone deficiency; consider lower start dose/slower titration in elderly pts, non-weight-based dosing in obese pts

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (cartridge): 5 mg per mL, 12 mg per mL; INJ (MiniQuick pre-filled syringe): 0.2 mg per 0.25 mL, 0.4 mg per 0.25 mL, 0.6 mg per 0.25 mL, 0.8 mg per 0.25 mL, 1 mg per 0.25 mL, 1.2 mg per 0.25 mL, 1.4 mg per 0.25 mL, 1.6 mg per 0.25 mL, 1.8 mg per 0.25 mL, 2 mg per 0.25

growth hormone deficiency

[0.16-0.24 mg/kg/wk SC divided 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

growth failure, Prader-Willi syndrome-associated

[0.24 mg/kg/wk SC divided 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

growth failure, SGA-associated

[0.48 mg/kg/wk SC divided 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

growth failure, Turner syndrome-associated

[0.33 mg/kg/wk SC divided 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

idiopathic short stature

[0.47 mg/kg/wk SC divided 6-7x/wk]

Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]