hydrochlorothiazide

Adult Dosing .

Dosage forms:  CAP: 12.5 mg; TAB: 12.5 mg, 25 mg, 50 mg

HTN

[12.5-50 mg PO qd]

Start: 12.5-25 mg PO qd; Max: 50 mg/day

edema

[25-100 mg PO qd]

Alt: may be dosed qod or 3-5x/wk; Info: in heart failure pts, start 25 mg PO qd-bid, max 200 mg/day

renal dosing

[see below]

CrCl <10: avoid use; anuria: contraindicated; Info: caution advised if severe impairment

HD/PD: avoid use

hepatic dosing

[see below]

hepatic impairment/progressive hepatic dz: not defined, caution advised

Peds Dosing .

Dosage forms:  TAB: 12.5 mg, 25 mg, 50 mg

HTN

[<6 mo]

Dose: 1-3 mg/kg/day PO divided bid; Max: 37.5 mg/day

[6 mo-2 yo]

Dose: 1-2 mg/kg/day PO divided qd-bid; Max: 37.5 mg/day

[2-12 yo]

Dose: 1-2 mg/kg/day PO divided qd-bid; Max: 100 mg/day

edema

[<6 mo]

Dose: 1-3 mg/kg/day PO divided bid; Max: 37.5 mg/day

[6 mo-2 yo]

Dose: 1-2 mg/kg/day PO divided qd-bid; Max: 37.5 mg/day

[2-12 yo]

Dose: 1-2 mg/kg/day PO divided qd-bid; Max: 100 mg/day

bronchopulmonary dysplasia (off-label)

[<24 mo]

Dose: 2-4 mg/kg/day PO divided bid

renal dosing

[see below]

CrCl <10: avoid use; anuria: contraindicated; Info: caution advised if severe impairment

HD/PD: avoid use

hepatic dosing

[see below]

hepatic impairment/progressive hepatic dz: not defined, caution advised