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oxytocin
generic
Black Box Warnings .
Not for Elective Labor Induction
not indicated for elective labor induction since inadequate data to evaluate benefit vs. risk; elective induction defined as labor initiation w/o medical indications
Adult Dosing .
Dosage forms: INJ
labor induction or augmentation
- [individualize dose IV]
- Start: 0.5-2 milliunits/min IV, incr. 1-2 milliunits/min q15-40min until contraction pattern estab.; Max: 20 milliunits/min (augmentation), 40 milliunits/min (induction); Alt: 6 milliunits/min IV, incr. 3-6 milliunits q15-40min, reduce increment if hyperstimulation occurs; Info: rates >9-10 milliunits/min rarely required at term, higher rates may be needed before term; mix 10 units/L IV fluid
postpartum hemorrhage
- [prevention]
- Dose: 10 units IM x1 after placenta delivery; Alt: 20 milliunits/min IV after placenta delivery until uterus firmly contracted; titrate rate to sustain contraction and control uterine atony; Info: mix 10-40 units/L IV fluid
- [treatment]
- Dose: 60-200 milliunits/min IV; Info: mix 10-40 units/L IV fluid
abortion adjunct
- [10-20 milliunits/min IV]
- Max: 30 units/12h; Info: for elective, inevitable, or incomplete abortion; mix 10 units/500 mL IV fluid
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.