Select a medication above to begin.
Depo-Provera CI
medroxyprogesterone acetate
Black Box Warnings .
BMD Loss
significant BMD loss possible; greater loss w/ incr. duration of use; may not be completely reversible; unknown if use during adolescence/early adulthood will decr. peak bone mass and incr. future osteoporotic fracture risk; only use as long-term birth control method (>2y) if other methods inadequate
Adult Dosing .
Dosage forms: INJ (pre-filled syringe): 150 mg per mL; INJ (vial): 150 mg per mL
contraception
- [150 mg IM q3mo]
- Start: w/in 5 days of menses onset, w/in 5 days postpartum, or >6wk postpartum if breastfeeding; Info: not recommended >2y unless inadequate tx alternatives
renal dosing
- [see below]
- renal dz: not defined, caution advised
- HD/PD: not defined, caution advised
hepatic dosing
- [see below]
- active hepatic dz: contraindicated
Peds Dosing .
- Dosage forms: INJ (pre-filled syringe): 150 mg per mL; INJ (vial): 150 mg per mL
contraception
- [postmenarchal females]
- Dose: 150 mg IM q3mo; Start: w/in 5 days of menses onset, w/in 5 days postpartum, or >6wk postpartum if breastfeeding; Info: not recommended >2y unless inadequate tx alternatives
renal dosing
- [see below]
- renal dz: not defined, caution advised
- HD/PD: not defined, caution advised
hepatic dosing
- [see below]
- active hepatic dz: contraindicated