Angiomax

Adult Dosing .

Dosage forms:  INJ

anticoagulation

[0.75 mg/kg/dose IV x1, then 1.75 mg/kg/h IV for procedure duration]

Info: for pts undergoing PCI, incl. pts w/ or w/o HIT/HITTS; may cont. 1.75 mg/kg/h IV up to 4h post-procedure for pts w/ STEMI; monitor ACT 5min after bolus and give 0.3 mg/kg/dose IV x1 if needed; use w/ aspirin 300-325 mg/day; may consider adding GP IIb/IIIa inhibitor

renal dosing

[see below]

CrCl <30: 0.75 mg/kg/dose x1, then 1 mg/kg/h

HD: 0.75 mg/kg/dose x1, then 0.25 mg/kg/h; supplement after dialysis not defined; PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

anticoagulation, intravascular procedure adjunct (off-label)

[0.75 mg/kg/dose IV x1, then 1.75 mg/kg/h IV for procedure duration]

Info: for pts w/ congenital heart dz; may cont. 0.25 mg/kg/h IV prn up to 72h post-procedure

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD: consider adult renal dosing for guidance; PD: not defined

hepatic dosing

[not defined]