fluticasone propionate/ salmeterol inhaled

Adult Dosing .

Dosage forms:  DPI: 55 mcg/14 mcg per actuation, 113 mcg/14 mcg per actuation, 232 mcg/14 mcg per actuation; 100 mcg/50 mcg per blister, 250 mcg/50 mcg per blister, 500 mcg/50 mcg per blister

asthma, maintenance tx

[DPI form w/ 14 mcg salmeterol]

Dose: 1 puff (55 mcg/14 mcg, 113 mcg/14 mcg, or 232 mcg/14 mcg per actuation) inhaled q12h; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 464 mcg/28 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[DPI form w/ 50 mcg salmeterol]

Dose: 1 puff (100 mcg/50 mcg, 250 mcg/50 mcg, or 500 mcg/50 mcg per blister) inhaled q12h; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 1000 mcg/100 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

COPD, maintenance tx

[1 puff (250 mcg/50 mcg per blister) inhaled q12h]

Info: search 'gold' for epocrates COPD GOLD decision tools

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  DPI: 55 mcg/14 mcg per actuation, 113 mcg/14 mcg per actuation, 232 mcg/14 mcg per actuation; 100 mcg/50 mcg per blister, 250 mcg/50 mcg per blister, 500 mcg/50 mcg per blister

asthma, maintenance tx

[DPI form w/ 50 mcg salmeterol, 4-11 yo]

Dose: 1 puff (100 mcg/50 mcg per blister) inhaled q12h; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[DPI form w/ 50 mcg salmeterol, 12 yo and older]

Dose: 1 puff (100 mcg/50 mcg, 250 mcg/50 mcg, or 500 mcg/50 mcg per blister) inhaled q12h; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 1000 mcg/100 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[DPI form w/ 14 mcg salmeterol, 12 yo and older]

Dose: 1 puff (55 mcg/14 mcg, 113 mcg/14 mcg, or 232 mcg/14 mcg per actuation) inhaled q12h; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 464 mcg/28 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised