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loxapine
generic
Black Box Warnings .
Dementia-Related Psychosis
not approved for dementia-related psychosis; incr. mortality risk in elderly pts on antipsychotic tx for dementia-related psychosis; most deaths due to cardiovascular or infectious events
Adult Dosing .
Dosage forms: CAP: 5 mg, 10 mg, 25 mg, 50 mg
psychosis
- [60-100 mg/day PO divided bid-qid]
- Start: 10 mg PO bid, titrate over 7-10 days; Max: 250 mg/day; Info: may start up to 50 mg/day in divided doses for severe sx; use lowest effective dose; D/C if ANC <1000; consider D/C if unexplained decr. in WBC
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.