galantamine

Adult Dosing .

Dosage forms:  ER CAP: 8 mg, 16 mg, 24 mg; TAB: 4 mg, 8 mg, 12 mg; SOL: 4 mg per mL

Alzheimer dz, mild-moderate dementia

[immediate-release form]

Dose: 8-12 mg PO bid; Start: 4 mg PO bid, incr. to 8 mg PO bid after at least 4wk, then may incr. to 12 mg PO bid after at least 4wk; Max: 24 mg/day; Info: retitrate from 4 mg PO bid if tx interrupted >3 days; give w/ food

[extended-release form]

Dose: 16-24 mg ER PO qam; Start: 8 mg ER PO qam, incr. to 16 mg ER PO qam after at least 4wk, then may incr. to 24 mg ER PO qam after at least 4wk; Max: 24 mg/day ER; Info: may convert from IR to ER form at same total daily dose; retitrate from 8 mg ER PO qam if tx interrupted >3 days; give w/ food

renal dosing

[see below]

CrCl 9-59: max 16 mg/day; CrCl <9: avoid use

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class B: max 16 mg/day; Child-Pugh Class C: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.