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dexmethylphenidate hydrochloride
generic
Black Box Warnings .
Abuse, Misuse, and Addiction
CNS stimulants have high potential for abuse and misuse, can lead to substance use disorder, incl. addiction; misuse and abuse can result in overdose and death, risk incr. w/ higher doses or unapproved admin. methods; assess risk for abuse, misuse, and addiction before prescribing and throughout tx; educate pts and families about risks and proper drug storage and disposal; monitor frequently for s/sx of abuse, misuse, and addiction during tx
Adult Dosing .
Dosage forms: ER CAP: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg; TAB: 2.5 mg, 5 mg, 10 mg
ADHD
- [immediate-release form]
- Dose: 2.5-10 mg PO bid; Start: 2.5 mg PO bid, then may incr. by 2.5-5 mg/day q7 days; Max: 20 mg/day; Info: duration 4-5h; space doses at least 4h apart; to convert from methylphenidate, start at 50% of current methylphenidate daily dose
- [extended-release form]
- Dose: 10-40 mg ER PO qam; Start: 10 mg ER PO qam, then may incr. by 10 mg/day q7 days; Max: 40 mg/day ER; Info: duration 8-12h; to convert from IR form, use same total daily dose; to convert from methylphenidate, start at 50% of current methylphenidate daily dose; may open ER cap, but do not crush/chew contents
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: ER CAP: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg; TAB: 2.5 mg, 5 mg, 10 mg
ADHD
- [immediate-release form, 6 yo and older]
- Dose: 2.5-10 mg PO bid; Start: 2.5 mg PO bid, then may incr. by 2.5-5 mg/day q7 days; Max: 20 mg/day; Info: duration 4-5h; space doses at least 4h apart; to convert from methylphenidate, start at 50% of current methylphenidate daily dose
- [extended-release form, 6 yo and older]
- Dose: 5-30 mg ER PO qam; Start: 5 mg ER PO qam, then may incr. by 5 mg/day q7 days; Max: 30 mg/day ER; Info: duration 8-12h; to convert from IR form, use same total daily dose; to convert from methylphenidate, start at 50% of current methylphenidate daily dose; may open ER cap, but do not crush/chew contents
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]