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Hemabate
carboprost tromethamine
Black Box Warnings .
Appropriate Use
strictly follow recommended dose; use only by medically trained personnel in hospital w/ ICU and surgical facilities
Adult Dosing .
Dosage forms: INJ: 250 mcg per mL
pregnancy termination, wk 13-20
- [250 mcg IM q90-210min]
- Start: 100 mcg IM test dose; Max: 12 mg total dose or use x2 days; Info: may incr. dose to 500 mcg if uterine contractility not adequate after several 250 mcg doses
postpartum hemorrhage
- [250 mcg IM x1]
- Max: 2 mg total dose; Info: may repeat q15-90min; for refractory bleeding
renal dosing
- [see below]
- renal impairment: contraindicated
- HD/PD: not defined
hepatic dosing
- [see below]
- acute impairment: contraindicated
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.