Lupron Depot

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 3.75 mg, 7.5 mg

endometriosis

[3.75 mg IM qmo for up to 6mo]

Max: 12mo; Info: may repeat 6mo tx course if sx recur, give w/ norethindrone acetate 5 mg PO qd for retreatment

uterine fibroids

[3.75 mg IM qmo for up to 3mo]

Info: for preop hematologic improvement in pts w/ anemia; use w/ iron

prostate CA

[advanced dz]

Dose: 7.5 mg IM qmo

[localized dz (off-label)]

Dose: 7.5 mg IM qmo; Info: for clinically localized dz as neoadjuvant, concurrent and/or adjuvant tx w/ XRT

transgender hormone therapy, feminizing (off-label)

[3.75-7.5 mg IM qmo]

Info: adjust dose based on pt tx goals, clinical response, and testosterone levels; refer to WPATH or Endocrine Society guidelines

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (pre-filled syringe): 3.75 mg

endometriosis

[postmenarchal females]

Dose: 3.75 mg IM qmo for up to 6mo; Max: 12mo; Info: may repeat 6mo tx course if sx recur, give w/ norethindrone acetate 5 mg PO qd for retreatment

uterine fibroids

[postmenarchal females]

Dose: 3.75 mg IM qmo for up to 3mo; Info: for preop hematologic improvement in pts w/ anemia; use w/ iron

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]