Invanz

Adult Dosing .

Dosage forms:  INJ

intra-abdominal infections, complicated

[1 g IM/IV qd x5-14 days]

skin/skin structure infections, complicated bacterial

[1 g IM/IV qd x7-14 days]

Info: includes diabetic foot infections w/o osteomyelitis

pneumonia, community-acquired

[1 g IM/IV qd for at least 5 days]

UTI, complicated

[1 g IM/IV qd x10-14 days]

gynecologic infections

[1 g IM/IV qd x3-10 days]

infection prophylaxis, colorectal surgery

[1 g IV x1]

Start: w/in 60min preop

renal dosing

[adjust dose amount]

CrCl <30: 500 mg qd

HD: 500 mg qd; give 150 mg as supplement after dialysis only if maint. dose given <6h prior to HD; PD: 500 mg qd; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

intra-abdominal infections, complicated

[3 mo-12 yo]

Dose: 30 mg/kg/day IM/IV divided bid x5-14 days; Max: 1 g/day

[13 yo and older]

Dose: 1 g IM/IV qd x5-14 days

skin/skin structure infections, complicated bacterial

[3 mo-12 yo]

Dose: 30 mg/kg/day IM/IV divided bid x7-14 days; Max: 1 g/day

[13 yo and older]

Dose: 1 g IM/IV qd x7-14 days

pneumonia, community-acquired

[3 mo-12 yo]

Dose: 30 mg/kg/day IM/IV divided bid x10-14 days; Max: 1 g/day

[13 yo and older]

Dose: 1 g IM/IV qd x10-14 days

UTI, complicated

[3 mo-12 yo]

Dose: 30 mg/kg/day IM/IV divided bid x10-14 days; Max: 1 g/day

[13 yo and older]

Dose: 1 g IM/IV qd x10-14 days

gynecologic infections

[3 mo-12 yo]

Dose: 30 mg/kg/day IM/IV divided bid x3-10 days; Max: 1 g/day

[13 yo and older]

Dose: 1 g IM/IV qd x3-10 days

infection prophylaxis, colorectal surgery (off-label)

[1 yo and older]

Dose: 15 mg/kg/dose IV x1; Start: w/in 60min preop; Max: 1000 mg/dose

renal dosing

[adjust dose amount]

CrCl <30: decr. usual divided dose by 50%

HD/PD: not defined, consider adult renal dosing for guidance

hepatic dosing

[not defined]