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haloperidol decanoate
generic
Black Box Warnings .
Dementia-Related Psychosis
not approved for dementia-related psychosis; incr. mortality risk in elderly pts on antipsychotic tx for dementia-related psychosis; most deaths due to cardiovascular or infectious events
Adult Dosing .
Dosage forms: INJ: 50 mg per mL, 100 mg per mL
Special Note
- [strength clarification]
- Info: 50 mg haloperidol equivalent to 70.52 mg haloperidol decanoate; all strengths expressed as haloperidol
psychosis, chronic
- [50-100 mg IM qmo]
- Start: 10-20x oral qd dose; if conversion >100 mg, give balance in 3-7 days; Max: 450 mg/mo; Info: gradually taper PO haloperidol; lower doses and slower titration in elderly, debilitated; taper dose gradually to D/C; D/C if ANC <1000; consider D/C if unexplained decr. in WBC
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.