Select a medication above to begin.
sulindac
generic
Black Box Warnings .
Cardiovascular Thrombotic Event
NSAIDs incr. risk of serious and potentially fatal cardiovascular thrombotic events, incl. MI and stroke; risk may occur early in tx and may incr. w/ duration of use; contraindicated in CABG periop setting
GI Bleeding, Ulceration, and Perforation
NSAIDs incr. risk of serious and potentially fatal GI adverse events incl. bleeding, ulcer, and stomach or intestine perforation; GI events may occur at any time during use and w/o warning sx; elderly pts and pts w/ hx of PUD or GI bleeding at greater risk for serious GI events
Adult Dosing .
Dosage forms: TAB: 150 mg, 200 mg
osteoarthritis
- [150-200 mg PO bid]
- Start: 150 mg PO bid; Max: 400 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs
rheumatoid arthritis
- [150-200 mg PO bid]
- Start: 150 mg PO bid; Max: 400 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs
gout, acute
- [150-200 mg PO bid x7 days]
- Start: 200 mg PO bid; Max: 400 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs
ankylosing spondylitis
- [150-200 mg PO bid]
- Start: 150 mg PO bid; Max: 400 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs
for anti-inflammatory uses
- [200 mg PO bid x7-14 days]
- Max: 400 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs
renal dosing
- [see below]
- mild-moderate impairment: decr. usual dose, amount not defined; severe impairment: avoid use; advanced renal dz: avoid use
- HD/PD: avoid use
hepatic dosing
- [see below]
- hepatic impairment: consider decr. usual dose
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.