trihexyphenidyl

Adult Dosing .

Dosage forms:  TAB: 2 mg, 5 mg; SOL: 2 mg per 5 mL

Parkinson dz

[6-10 mg/day PO divided tid]

Start: 1 mg PO qd x1 day, then 2 mg PO qd; incr. 2 mg q3-5 days; Max: 15 mg/day; Info: give w/ food; doses >10 mg/day divide qid; taper dose gradually to D/C

extrapyramidal sx

[5-15 mg/day PO divided tid-qid]

Start: 1 mg PO qd x1, repeat in several hours prn; Max: 15 mg/day; Info: give w/ food; doses >10 mg/day divide qid; taper dose gradually to D/C

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  TAB: 2 mg, 5 mg; SOL: 2 mg per 5 mL

dystonia, generalized (off-label)

[2 yo and older]

Dose: 6-40 mg/day PO divided tid-qid; Start: 1 mg PO bid x7 days, then incr. by 1-2 mg/day q3-4 days; Max: 100 mg/day; Info: give w/ food; doses >10 mg/day divide qid; taper dose gradually to D/C

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance