griseofulvin microsize

Adult Dosing .

Dosage forms:  TAB: 500 mg; SUSP: 125 mg per 5 mL

onychomycosis

[1000 mg/day PO divided qd-qid]

Max: 1 g/day; Info: give for >4mo if fingernail infection; give for >6mo if toenail infection; give w/ high fat meal

tinea pedis

[1000 mg/day PO divided qd-qid x4-8wk]

Max: 1 g/day; Info: use w/ topical antifungal tx; give w/ high fat meal

tinea corporis or cruris

[500 mg/day PO divided qd-qid x2-4wk]

Max: 1 g/day; Info: give w/ high fat meal

tinea capitis

[500 mg/day PO divided qd-qid x4-6wk]

Max: 1 g/day; Info: give w/ high fat meal

tinea barbae

[500 mg/day PO divided qd-qid x4-8wk]

Max: 1 g/day; Info: give w/ high fat meal

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[see below]

hepatic failure: contraindicated

Peds Dosing .

Dosage forms:  TAB: 500 mg; SUSP: 125 mg per 5 mL

onychomycosis

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give for >4mo if fingernail infection; give for >6mo if toenail infection; give w/ high fat meal

tinea pedis

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give x4-8wk and use w/ topical antifungal tx; give w/ high fat meal

tinea cruris

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give x2-6wk; give w/ high fat meal

tinea capitis

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give x4-6wk; give w/ high fat meal

tinea corporis

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give 2-4wk; give w/ high fat meal

tinea barbae

[>2 yo]

Dose: 10-20 mg/kg/day PO divided qd-qid; Max: 1 g/day; Info: give >6wk; give w/ high fat meal

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

hepatic dosing

[see below]

hepatic failure: contraindicated