glucagon

Adult Dosing .

Dosage forms:  INJ: 1 mg per vial

Special Note

[Emergency Kit for Low Blood Sugar]

Info: kit contains glucagon 1 mg per vial x1, sterile water 1 mL pre-filled syringe x1; recommended reconstitution yields 1 mg per mL

[Diagnostic Kit]

Info: kit contains glucagon 1 mg per vial x1, sterile water 1 mL per vial x1; recommended reconstitution yields 1 mg per mL

hypoglycemia, severe

[1 mg SC/IM/IV x1]

Info: may repeat dose x1 after 15min

GI motility inhibition, diagnostic GI imaging

[stomach or small bowel]

Dose: 0.2-0.5 mg IV x1; Alt: 1-2 mg IM x1; Info: refer to institutional protocol

[colon]

Dose: 0.5-0.75 mg IV x1; Alt: 1-2 mg IM x1; Info: refer to institutional protocol

beta blocker overdose (off-label)

[3-5 mg/h IV]

Start: 3-10 mg IV x1; Alt: 0.05-0.15 mg/kg/dose IV x1, then 0.05-0.1 mg/kg/h IV

calcium channel blocker overdose (off-label)

[1-10 mg/h IV]

Start: 3-10 mg IV x1, may repeat x1 if no BP response in 10min; Info: start infusion only if BP response from loading doses

anaphylaxis (off-label)

[0.3-0.9 mg/h IV]

Start: 1-2 mg IV x1; Info: for pts not responsive to beta agonists due to beta blocker use

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ: 1 mg per vial

Special Note

[Emergency Kit for Low Blood Sugar]

Info: kit contains glucagon 1 mg per vial x1, sterile water 1 mL pre-filled syringe x1; recommended reconstitution yields 1 mg per mL

hypoglycemia, severe

[<6 yo or <25 kg]

Dose: 0.5 mg SC/IM/IV x1; Alt: 0.02-0.03 mg/kg/dose SC/IM/IV x1; Info: may repeat dose x1 after 15min

[6 yo and older or >25 kg]

Dose: 1 mg SC/IM/IV x1; Info: may repeat dose x1 after 15min

beta blocker overdose (off-label)

[2-12 yo]

Dose: 0.07 mg/kg/h IV; Start: 0.03-0.15 mg/kg/dose IV x1; Max: 5 mg/h

[13-17 yo]

Dose: 1-5 mg/h IV; Start: 5-10 mg IV x1

calcium channel blocker overdose (off-label)

[2-12 yo]

Dose: 0.05-0.1 mg/kg/h IV; Start: 0.05 mg/kg/dose IV x1, may repeat x1 if no BP response in 10min; Info: start infusion only if BP response from loading doses

[13-17 yo]

Dose: 1-5 mg/h IV; Start: 5-10 mg IV x1, may repeat x1 if no BP response in 10min; Info: start infusion only if BP response from loading doses

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]