Novolin N

Adult Dosing .

Dosage forms:  INJ (FlexPen U-100 pen, FlexPen ReliOn U-100 pen): 100 units per mL; INJ (U-100 vial, ReliOn U-100 vial): 100 units per mL

Special Note

[additional info]

Info: search Insulin Product Comparisons for comparison of onset, peak, duration, dosage form, and mixing compatibility

diabetes mellitus, type 1

[individualize dose SC bid]

Start: approx. 40-50% of total daily insulin requirement; Info: usual total daily insulin requirement 0.4-1 units/kg/day (basal + prandial); use w/ rapid-acting or short-acting insulin; dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 1-2h, peak 4-14h, duration 10-24h (intermediate-acting insulin)

diabetes mellitus, type 2

[individualize dose SC qd-bid]

Start: 10 units SC qd; Alt: 0.1-0.2 units/kg/dose SC qd; Info: dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 1-2h, peak 4-14h, duration 10-24h (intermediate-acting insulin)

renal dosing

[see below]

renal impairment: consider decr. usual start dose

HD/PD: consider decr. usual start dose; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  INJ (FlexPen U-100 pen, FlexPen ReliOn U-100 pen): 100 units per mL; INJ (U-100 vial, ReliOn U-100 vial): 100 units per mL

Special Note

[additional info]

Info: search Insulin Product Comparisons for comparison of onset, peak, duration, dosage form, and mixing compatibility

diabetes mellitus, type 1

[individualize dose SC bid]

Start: approx. 30-45% of total daily insulin requirement; Info: usual total daily insulin requirement 0.4-1 units/kg/day (basal + prandial); adolescents may require higher doses; use w/ rapid-acting or short-acting insulin; onset 1-2h, peak 4-14h, duration 10-24h (intermediate-acting insulin)

diabetes mellitus, type 2

[individualize dose SC qd-bid]

Start: 10 units SC qd; Alt: 0.1-0.2 units/kg/dose SC qd; Info: start 0.25-0.5 units/kg/dose SC qd in pts w/ A1c >8.5% or ketosis; onset 1-2h, peak 4-14h, duration 10-24h (intermediate-acting insulin)

renal dosing

[see below]

renal impairment: consider decr. usual start dose

HD/PD: consider decr. usual start dose; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised