Select a medication above to begin.
Accupril
quinapril
Black Box Warnings .
Fetal Toxicity
fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected
Adult Dosing .
Dosage forms: TAB: 5 mg, 10 mg, 20 mg, 40 mg
HTN
- [10-80 mg/day PO divided qd-bid]
- Start: 10-20 mg PO qd, may incr. dose no more frequently than q2wk; Info: start 5 mg PO qd if also on diuretic; start 10 mg PO qd in elderly pts
heart failure w/ reduced ejection fraction
- [20 mg PO bid]
- Start: 5 mg PO bid, may incr. dose qwk
renal dosing
- [HTN]
- CrCl 61-89: start 10 mg qd; CrCl 30-60: start 5 mg qd; CrCl 10-29: start 2.5 mg qd; CrCl <10: not defined
- HD/PD: not defined
- [heart failure w/ reduced ejection fraction]
- CrCl 31-89: start 5 mg qd; CrCl 10-30: start 2.5 mg qd; CrCl <10: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: TAB: 5 mg, 10 mg, 20 mg, 40 mg
HTN (off-label)
- [1-17 yo]
- Dose: 5-80 mg/day PO divided qd-bid; Start: 5-10 mg PO qd, may incr. dose no more frequently than q2wk; Max: 80 mg/day
renal dosing
- [not defined]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: consider adult renal dosing for guidance
hepatic dosing
- [not defined]
- hepatic impairment: consider adult hepatic dosing for guidance