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Chemet
succimer
Adult Dosing .
Dosage forms: CAP: 100 mg
lead poisoning (off-label)
- [10 mg/kg/dose PO q8h x5 days, then q12h x14 days]
- Alt: 350 mg/m^2/dose PO q8h x5 days, then q12h x14 days; Info: for pts w/ mild symptoms or blood lead level 70-100 mcg/dL; may repeat tx course >q2wk; may sprinkle in soft food or juice; maintain adequate hydration/urine output before and during tx; hold or D/C if ANC <1200
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
- Dosage forms: CAP: 100 mg
lead poisoning
- [1 yo and older]
- Dose: 10 mg/kg/dose PO q8h x5 days, then q12h x14 days; Alt: 350 mg/m^2/dose PO q8h x5 days, then q12h x14 days; Info: for asymptomatic pts w/ blood lead level 45-69 mcg/dL; may repeat tx course >q2wk; may sprinkle in soft food or juice; maintain adequate hydration/urine output before and during tx; hold or D/C if ANC <1200
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised