rosuvastatin

Adult Dosing .

Dosage forms:  TAB: 5 mg, 10 mg, 20 mg, 40 mg

primary hyperlipidemia

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

heterozygous familial hypercholesterolemia

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

homozygous familial hypercholesterolemia

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

hypertriglyceridemia

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

primary dysbetalipoproteinemia

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

cardiovascular event risk reduction

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

atherosclerotic cardiovascular dz

[5-40 mg PO qd]

Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels); search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

renal dosing

[adjust dose amount]

CrCl <30: start 5 mg qd, max 10 mg qd

HD: consider decr. usual dose, max 10 mg qd; no supplement after dialysis; PD: not defined

hepatic dosing

[see below]

acute hepatic failure or decompensated cirrhosis: contraindicated

Peds Dosing .

Dosage forms:  TAB: 5 mg, 10 mg, 20 mg, 40 mg

heterozygous familial hypercholesterolemia

[8-9 yo]

Dose: 5-10 mg PO qd; Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels)

[10 yo and older]

Dose: 5-20 mg PO qd; Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels)

homozygous familial hypercholesterolemia

[7 yo and older]

Dose: 20 mg PO qd; Info: may adjust dose q4wk; start 5 mg PO qd in Asian pts (risk of incr. drug levels)

renal dosing

[adjust dose amount]

CrCl <30: start 5 mg qd, max 10 mg qd

HD: consider decr. usual dose, max 10 mg qd; no supplement after dialysis; PD: not defined

hepatic dosing

[see below]

acute hepatic failure or decompensated cirrhosis: contraindicated