Reyataz

Adult Dosing .

Dosage forms:  CAP: 200 mg, 300 mg; PWDR: 50 mg per pkt

HIV infection, tx-naive

[boosted regimen]

Dose: 300 mg PO qd; Info: give w/ ritonavir 100 mg PO qd or cobicistat 150 mg PO qd; do not open cap; give w/ food

[unboosted regimen]

Dose: 400 mg PO qd; Info: give w/ food; do not open cap

HIV infection, tx-experienced

[300 mg PO qd]

Info: give w/ ritonavir 100 mg PO qd or cobicistat 150 mg PO qd; do not open cap; give w/ food

renal dosing

[tx-naive]

renal impairment: no adjustment

HD: 300 mg qd w/ ritonavir 100 mg qd; no supplement after dialysis; PD: not defined

[tx-experienced]

renal impairment: no adjustment

HD: avoid use; PD: not defined

hepatic dosing

[tx-naive]

Child-Pugh Class B: 300 mg qd; Child-Pugh Class C: avoid use; Info: avoid use w/ ritonavir in hepatic impairment

[tx-experienced]

hepatic impairment: not defined

Peds Dosing .

Dosage forms:  CAP: 200 mg, 300 mg; PWDR: 50 mg per pkt

Special Note

[formulation clarification]

Info: oral pwdr and capsules not interchangeable

HIV infection

[oral pwdr form, 3 mo and older, 15-24.9 kg]

Dose: 250 mg pwdr PO qd; Info: give w/ ritonavir 100 mg PO qd; give w/ food

[oral pwdr form, 3 mo and older, >25 kg]

Dose: 300 mg pwdr PO qd; Info: give w/ ritonavir 100 mg PO qd; give w/ food

[capsule form, 6-17 yo, 15-34.9 kg]

Dose: 200 mg cap PO qd; Info: give w/ ritonavir 100 mg PO qd; do not open cap; give w/ food

[capsule form, 6-17 yo, >35 kg]

Dose: 300 mg cap PO qd; Info: give w/ ritonavir 100 mg PO qd or cobicistat 150 mg PO qd; do not open cap; give w/ food

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance