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Sensipar
cinacalcet
Adult Dosing .
Dosage forms: TAB: 30 mg, 60 mg, 90 mg
hyperparathyroidism, secondary
- [30-180 mg PO qd]
- Start: 30 mg PO qd, may incr. dose q2-4wk by 30 mg/day up to 120 mg PO qd, then to 180 mg PO qd; Info: for pts w/ CKD on dialysis; see pkg insert for dose adjustments based on iPTH, Ca, PO4 levels; give w/ food; do not cut/crush/chew tab
hypercalcemia, parathyroid CA-assoc.
- [individualize dose PO bid-qid]
- Start: 30 mg PO bid, may incr. dose q2-4wk by 30 mg/dose up to 90 mg PO bid, then to 90 mg PO tid-qid; Info: adjust dose based on Ca levels; give w/ food; do not cut/crush/chew tab
severe hypercalcemia, primary hyperparathyroidism-assoc.
- [individualize dose PO bid-qid]
- Start: 30 mg PO bid, may incr. dose q2-4wk by 30 mg/dose up to 90 mg PO bid, then to 90 mg PO tid-qid; Info: for pts unable to undergo parathyroidectomy; adjust dose based on Ca levels; give w/ food; do not cut/crush/chew tab
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [see below]
- Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined, caution advised
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.