Xifaxan

Adult Dosing .

Dosage forms:  TAB: 200 mg, 550 mg

traveler's diarrhea, E. coli-induced

[200 mg PO tid x3 days]

hepatic encephalopathy

[550 mg PO bid]

IBS, diarrhea-predominant

[550 mg PO tid x14 days]

Info: may repeat dose up to 2x if recurrent dz

recurrent C. difficile infection, adjunct (off-label)

[400 mg PO tid x20 days]

Info: for 2 or more recurrences; give after 10 days of vancomycin PO

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined, caution advised

Peds Dosing .

Dosage forms:  TAB: 200 mg

traveler's diarrhea, E. coli-induced

[12 yo and older]

Dose: 200 mg PO tid x3 days

recurrent C. difficile infection, adjunct (off-label)

[3 yo and older]

Dose: 200 mg PO tid x14 days; Info: for 2 or more recurrences; give after 14 days of vancomycin PO

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined, caution advised