ramipril

Adult Dosing .

Dosage forms:  CAP: 1.25 mg, 2.5 mg, 5 mg, 10 mg

HTN

[2.5-20 mg/day PO divided qd-bid]

Start: 2.5 mg PO qd; Info: start 1.25 mg PO qd if hypovolemia or renal artery stenosis

heart failure, post-MI

[5 mg PO bid]

Start: 2.5 mg PO bid, may incr. dose q3wk; Info: start 1.25 mg PO qd if hypovolemia or renal artery stenosis

cardiovascular event risk reduction

[10 mg PO qd]

Start: 2.5 mg PO qd x7 days, then 5 mg PO qd x3wk, then 10 mg PO qd; Info: for pts 55 yo and older w/ CAD, stroke, PVD, or DM hx plus 1 other risk factor; start 1.25 mg PO qd if hypovolemia or renal artery stenosis; may divide dose bid if MI or HTN

heart failure w/ reduced ejection fraction (off-label)

[10 mg PO qd]

Start: 1.25-2.5 mg PO qd, may incr. dose q1-2wk

renal dosing

[HTN]

CrCl <40: start 1.25 mg qd, max 5 mg/day

HD: 1.25-5 mg qd; no supplement after dialysis; PD: 1.25-5 mg qd; supplement not defined

[heart failure, post-MI]

CrCl <40: start 1.25 mg qd, then may incr. to 1.25 mg bid, max 2.5 mg bid

HD: 1.25-5 mg/day divided qd-bid; no supplement after dialysis; PD: 1.25-5 mg/day divided qd-bid; supplement not defined

[all other indications]

CrCl <40: decr. usual dose by 75%

HD: 1.25-5 mg qd; no supplement after dialysis; PD: 1.25-5 mg qd; supplement not defined

hepatic dosing

[see below]

severe cirrhosis or ascites: not defined, caution advised

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.