erythromycin lactobionate

Adult Dosing .

Dosage forms:  INJ

infections, bacterial

[15-20 mg/kg/day IV divided q6h]

Max: 4 g/day; Info: dose, duration varies w/ infection type, severity

gastroparesis, severe (off-label)

[3 mg/kg/dose IV q8h]

delayed gastric emptying (off-label)

[70-200 mg IV x1]

Alt: 200-250 mg IV q6-12h x1-3 days; Info: for critically ill pts intolerant to enteral feeding

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  INJ

infections, bacterial

[infants/children]

Dose: 15-20 mg/kg/day IV divided q6h; Max: 4 g/day; Info: dose, duration varies w/ infection type, severity

community-acquired pneumonia, mod-severe atypical

[>3 mo]

Dose: 20 mg/kg/day IV divided q6h x10 days; Max: 4 g/day; Info: may switch to PO regimen when possible to complete course

GI dysmotility (off-label)

[children]

Dose: 3 mg/kg/h IV; Info: switch to PO tx ASAP

renal dosing

[GI dysmotility]

renal impairment: not defined

HD/PD: not defined

[all other indications]

CrCl <10: give 50-75% usual dose q8-12h

HD: give 50-75% usual dose q8-12h; no supplement after dialysis; PD: give 50-75% usual dose q8-12h; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised