Select a medication above to begin.
rocuronium
generic
Adult Dosing .
Dosage forms: INJ
endotracheal intubation
- [0.6 mg/kg/dose IV x1]
- Info: range 0.45-1.2 mg/kg/dose IV x1; use ABW in obese pts; onset 1-2min, 25% recovery 31min, range 22-67min (short to intermediate-acting)
rapid sequence intubation
- [1-1.2 mg/kg/dose IV x1]
- Start: immediately after induction agent; Info: use ABW in obese pts; onset <2min, 25% recovery 31-67min (short to intermediate-acting); wait 60sec to perform laryngoscopy and intubate; see Rapid Sequence Intubation (RSI), Adult table
neuromuscular blockade induction
- [0.6 mg/kg/dose IV x1]
- Info: range 0.45-1.2 mg/kg/dose IV x1; use ABW in obese pts; onset 1-2min, 25% recovery 31min, range 22-67min (short to intermediate-acting)
neuromuscular blockade maintenance
- [0.1-0.2 mg/kg/dose IV prn]
- Alt: 10-12 mcg/kg/min IV, then 4-16 mcg/kg/min IV; Info: individualize dose; use ABW in obese pts; consider decr. infusion rate 30-50% at 45-60min after induction dose if under isoflurane or enflurane anesthesia; give bolus dose or start infusion at early evidence of spontaneous recovery from induction dose, see pkg insert for dose timing details; peripheral nerve stimulator recommended to assess dose response and recovery
renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
- Dosage forms: INJ
neuromuscular blockade induction
- [<17 yo]
- Dose: 0.6 mg/kg/dose IV x1; Info: may decr. dose to 0.45 mg/kg based on anesthetic technique and pt age; onset <1min, 25% recovery 41min (3-12 mo), 27min (1-12 yo) (short to intermediate-acting)
neuromuscular blockade maintenance
- [<17 yo, isoflurane/nitrous oxide anesthesia]
- Dose: 0.15 mg/kg/dose IV prn; Alt: 7-10 mcg/kg/min IV; Info: individualize dose; give bolus dose or start infusion at early evidence of spontaneous recovery from induction dose, see pkg insert for dose timing details; peripheral nerve stimulator recommended to assess dose response and recovery
- [3 mo-14 yo, halothane anesthesia]
- Dose: 0.075-0.125 mg/kg/dose IV prn; Alt: 12 mcg/kg/min IV; Info: individualize dose; use lowest bolus dose for neonates, higher dose for pts 2-11 yo; give bolus doses or start infusion at early evidence of spontaneous recovery from induction dose, see pkg insert for dose timing details; peripheral nerve stimulator recommended to assess dose response and recovery
renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised