Mycamine

Adult Dosing .

Dosage forms:  INJ

candidemia

[100 mg IV q24h]

candidiasis, acute disseminated

[100 mg IV q24h]

candidal peritonitis and abscesses

[100 mg IV q24h]

candidiasis, esophageal

[150 mg IV q24h]

candidiasis prophylaxis, stem cell transplant

[50 mg IV q24h]

candidiasis, oropharyngeal (off-label)

[100 mg IV q24h]

Info: for fluconazole-refractory dz

endocarditis, candidal (off-label)

[150 mg IV q24h]

Info: for native valve endocarditis; not 1st-line agent; refer to IDSA and AHA guidelines

febrile neutropenia (off-label)

[100-150 mg IV q24h]

Info: for empiric tx in high-risk pts w/ persistent fever

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

candidemia

[<4 mo]

Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination

[4 mo and older]

Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

candidiasis, acute disseminated

[<4 mo]

Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination

[4 mo and older]

Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

candidal peritonitis and abscesses

[<4 mo]

Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination

[4 mo and older]

Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

candidiasis, esophageal

[4 mo and older, <31 kg]

Dose: 3 mg/kg/dose IV q24h

[4 mo and older, >31 kg]

Dose: 2.5 mg/kg/dose IV q24h; Max: 150 mg/day

candidiasis prophylaxis, stem cell transplant

[4 mo and older]

Dose: 1 mg/kg/dose IV q24h; Max: 50 mg/day

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]