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Ambien CR
zolpidem
Black Box Warnings .
Complex Sleep Behaviors
complex sleep behaviors may occur, incl. sleep-walking, sleep-driving, and engaging in other activities while not fully awake; may result in serious injuries, incl. death; D/C immediately if pt experiences a complex sleep behavior
Adult Dosing .
Dosage forms: ER TAB: 6.25 mg, 12.5 mg
insomnia, short-term tx
- [female pts]
- Dose: 6.25 mg PO qhs; Max: 12.5 mg/day; Info: for sleep onset and/or maintenance; use lowest effective dose, shortest possible tx duration; give immediately before bedtime and >7h before planned awakening; give 6.25 mg PO qhs in elderly or debilitated pts; give on empty stomach; do not cut/crush/chew tab; reevaluate if insomnia persists after 7-10 days of tx; taper dose gradually to D/C if prolonged use
- [male pts]
- Dose: 6.25-12.5 mg PO qhs; Max: 12.5 mg/day; Info: for sleep onset and/or maintenance; use lowest effective dose, shortest possible tx duration; give immediately before bedtime and >7h before planned awakening; give 6.25 mg PO qhs in elderly or debilitated pts; give on empty stomach; do not cut/crush/chew tab; reevaluate if insomnia persists after 7-10 days of tx; taper dose gradually to D/C if prolonged use
renal dosing
- [see below]
- renal impairment: no adjustment
- HD: no adjustment; no supplement; PD: not defined
hepatic dosing
- [see below]
- mild-moderate impairment: 6.25 mg qhs; severe impairment: avoid use
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.