Havrix

Adult Dosing .

Dosage forms:  INJ

hepatitis A dz prevention

[1 mL IM x2 doses 6-12mo apart]

Start: w/in 2wk prior to expected HAV exposure; Info: may give initial dose w/ 0.1-0.2 mL/kg immune globulin (human) for travel to endemic areas w/in 2wk if pts >40 yo, immunocompromised, chronic liver dz, other chronic conditions; search 'immunization' for epocrates Adult Immunization and CDC Pre-Travel Vaccine decision tools incl. links to CDC/ACIP schedules and recommendations

hepatitis A post-exposure prophylaxis (off-label)

[1 mL IM x1]

Start: w/in 2wk of exposure; Info: for pts who have not previously completed the 2-dose hepatitis A vaccine series; may give w/ 0.1 mL/kg immune globulin (human) in pts >40 yo; give w/ 0.1 mL/kg immune globulin (human) if immunocompromised, chronic liver dz, other chronic conditions; give 2nd dose per schedule to complete vaccine series

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

hepatitis A dz prevention

[12 mo and older]

Dose: 0.5 mL IM x2 doses at least 6-12mo apart; Start: w/in 2wk prior to expected HAV exposure; Info: may give w/ 0.1-0.2 mL/kg immune globulin (human) if immunocompromised, chronic liver dz, other chronic conditions; search 'immunization' for epocrates Child/Adolescent Immunization and CDC Pre-Travel Vaccine decision tools incl. links to CDC/ACIP schedules and recommendations

hepatitis A prophylaxis (off-label)

[pre-exposure, 6 mo and older]

Dose: 0.5 mL IM x1; Info: for pts traveling to endemic countries; not counted toward routine 2-dose series if 6-11 mo; may give w/ 0.1-0.2 mL/kg immune globulin (human) in pts 12 mo and older if immunocompromised, chronic liver dz, other chronic conditions; search 'immunization' for epocrates CDC Pre-Travel Vaccine decision tools incl. links to CDC recommendations

[post-exposure]

Dose: 0.5 mL IM x1; Start: w/in 2wk of exposure; Info: for pts 12 mo and older who have not previously completed the 2-dose hepatitis A series; give w/ 0.1 mL/kg immune globulin (human) if immunocompromised, chronic liver dz, other chronic conditions; give 2nd dose per schedule to complete routine vaccine series

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]