Azulfidine

Adult Dosing .

Dosage forms:  TAB: 500 mg

ulcerative colitis, mild-moderate

[500 mg PO q6h]

Start: 1 g PO q6-8h; Max: 4 g/day; Info: for induction or remission maintenance tx; start 500 mg PO q6-12h if GI intolerance; give w/ food

Crohn dz, mild-moderate (off-label)

[3-6 g/day PO divided q8h]

Info: give w/ food

rheumatoid arthritis (off-label)

[1 g PO q12h]

Max: 4 g/day; Info: start 0.5-1 g/day PO divided q12h if GI intolerance, then incr. dose over 4wk; give w/ food

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  TAB: 500 mg

ulcerative colitis, mild-moderate

[6 yo and older]

Dose: 30 mg/kg/day PO divided q6h; Start: 40-60 mg/kg/day PO divided q4-8h; Max 4 g/day; Info: for induction or remission maintenance tx; give w/ food

juvenile idiopathic arthritis (off-label)

[6 yo and older]

Dose: 30-50 mg/kg/day PO divided q12h; Start: 10 mg/kg/day PO divided q12h, then incr. over 4wk; Max: 2 g/day; Info: give w/ food

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised