Pneumovax 23

Adult Dosing .

Dosage forms:  INJ

invasive pneumococcal dz prevention

[no or unknown pneumococcal vaccine hx]

Dose: 0.5 mL SC/IM x1; Info: for pts 65 yo and older and high-risk pts <65 yo; give at least 8wk after last PCV15 dose in pts w/ cochlear implant, CSF leak, or immunocompromised pts, otherwise give at least 1y after last PCV13 or PCV15 dose; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV7 only]

Dose: 0.5 mL SC/IM x1; Info: for pts 65 yo and older and high-risk pts <65 yo; give at least 8wk after last PCV15 dose in pts w/ cochlear implant, CSF leak, or immunocompromised pts, otherwise give at least 1y after last PCV13 or PCV15 dose; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 only, <65 yo, pts w/ chronic conditions]

Dose: 0.5 mL SC/IM x1; Start: >1y after last PCV13 dose; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 only, <65 yo, pts w/ cochlear implant or CSF leak]

Dose: 0.5 mL SC/IM x1; Start: >8wk after last PCV13 dose; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 only, <65 yo, immunocompromised pts]

Dose: 0.5 mL SC/IM x2 doses >5y apart; Start: >8wk after last PCV13 dose; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 only, 65 yo and older]

Dose: 0.5 mL SC/IM x1; Start: >1y after last PCV13 dose; Info: give >8wk after last PCV13 dose in pts w/ cochlear implant, CSF leak, or immunocompromised pts; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 and PPSV23, <65 yo, immunocompromised pts]

Dose: 0.5 mL SC/IM x1; Start: >5y after last PPSV23 dose and >8wk after last PCV13 dose; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[previously received PCV13 and PPSV23, 65 yo and older]

Dose: 0.5 mL SC/IM x1; Info: for pts who received PPSV23 at <65 yo; give at least 5y after last PPSV23 dose; give at least 8wk after last PCV13 dose in pts w/ cochlear implant, CSF leak, or immunocompromised pts, otherwise give at least 1y after last PCV13 dose; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

invasive pneumococcal dz prevention

[2 yo and older at series start, pts w/ chronic conditions]

Dose: 0.5 mL SC/IM x1; Start: >8wk after last PCV13 or PCV15 dose; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[2 yo and older at series start, pts w/ CSF leak or cochlear implant]

Dose: 0.5 mL SC/IM x1; Start: >8wk after last PCV13 or PCV15 dose; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[2 yo and older at series start, immunocompromised pts]

Dose: 0.5 mL SC/IM x2 doses at least 5y apart; Start: >8wk after last PCV13 or PCV15 dose; may give PCV20 instead of 2nd PPSV23 dose; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]