Vivitrol

Adult Dosing .

Dosage forms:  INJ: 95 mg per mL

Special Note

[prescribing info]

Info: consider prescribing naloxone in pts w/ opioid use disorder

alcohol dependence

[380 mg IM q4wk]

Info: must be opioid free x7-14 days before tx start; consider naloxone challenge test if risk of withdrawal suspected; D/C tx 1mo before surgery w/ anticipated opioid use

opioid dependence

[380 mg IM q4wk]

Info: for prevention of relapse following opioid detoxification; must be opioid free x7-14 days before tx start; consider naloxone challenge test if risk of withdrawal suspected; D/C tx 1mo before surgery w/ anticipated opioid use

renal dosing

[see below]

CrCl 50-80: no adjustment; CrCl <50: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

Peds Dosing .

Dosage forms:  INJ: 95 mg per mL

Special Note

[prescribing info]

Info: consider prescribing naloxone in pts w/ opioid use disorder

opioid dependence (off-label)

[adolescents]

Dose: 380 mg IM q4wk; Info: for prevention of relapse following opioid detoxification; must be opioid free x7-14 days before tx start; consider naloxone challenge test if risk of withdrawal suspected; D/C tx 1mo before surgery w/ anticipated opioid use

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance