praziquantel

Adult Dosing .

Dosage forms:  TAB: 600 mg

schistosomiasis

[20 mg/kg/dose PO tid x1 day]

Info: separate doses by 4-6h; give w/ food; do not chew tab

liver flukes

[25 mg/kg/dose PO tid x1-2 days]

Info: separate doses by 4-6h; give w/ food; do not chew tab

cysticercosis (off-label)

[50 mg/kg/day PO divided q8h x14 days]

Info: give w/ food; do not chew tab

tapeworms (off-label)

[5-25 mg/kg/dose PO x1]

Info: give w/ food; do not chew tab

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined, caution advised

Peds Dosing .

Dosage forms:  TAB: 600 mg

schistosomiasis

[1 yo and older]

Dose: 20 mg/kg/dose PO bid-tid x1 day; Info: separate doses by 4-6h; give w/ food; do not chew tab

liver flukes

[1 yo and older]

Dose: 25 mg/kg/dose PO tid x1-2 days; Info: separate doses by 4-6h; give w/ food; do not chew tab

cysticercosis (off-label)

[1 yo and older]

Dose: 50 mg/kg/day PO divided q8h x14 days; Info: give w/ food; do not chew tab

tapeworms (off-label)

[1 yo and older]

Dose: 5-25 mg/kg/dose PO x1; Info: give w/ food; do not chew tab

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined, caution advised