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norethindrone/ ethinyl estradiol

generic

Drug Monograph

Black Box Warnings
Adult Dosing
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Black Box Warnings .

Smoking and Cardiovascular Events

cigarette smoking incr. risk of serious cardiovascular events from combined hormonal contraceptive use; incr. risk w/ age (particularly for women >35 yo) and w/ number of cigarettes smoked; contraindicated in smokers >35 yo

Adult Dosing .

Dosage forms: 20 mcg EE monophasic 21-day pack; 20 mcg EE monophasic 28-day pack (cap); 20 mcg EE monophasic 28-day pack (tab); 20 mcg EE monophasic 28-day pack (chewable tab); 25 mcg EE monophasic 28-day pack; 30 mcg EE monophasic 21-day pack; 30 mcg EE monophasic 28-day pack; 35 mcg EE monophasic 28-day pack

Special Note

[20 mcg EE monophasic 21-day pack components]: Info: 21-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x21

[20 mcg EE monophasic 28-day pack (cap) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg cap x24, then ferrous fumarate 75 mg cap x4

[20 mcg EE monophasic 28-day pack (tab) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x21, then ferrous fumarate 75 mg tab x7; 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x24, then ferrous fumarate 75 mg tab x4

[20 mcg EE monophasic 28-day pack (chewable tab) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg chewable tab x24, then ferrous fumarate 75 mg tab x4

[25 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 0.8 mg/25 mcg chewable tab x24, then ferrous fumarate 75 mg chewable tab x4

[30 mcg EE monophasic 21-day pack components]: Info: 21-day pack contains norethindrone/ethinyl estradiol 1.5 mg/30 mcg tab x21

[30 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1.5 mg/30 mcg tab x21, then ferrous fumarate 75 mg tab x7

[35 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 0.4 mg/35 mcg chewable tab x21, then ferrous fumarate 75 mg tab x7

[additional info]: Info: see Oral Contraceptive Pill (OCP) Hormonal Activity and Therapeutic Equivalence table

contraception

[20 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap)]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

dysfunctional uterine bleeding, moderate (off-label)

[30 mcg EE monophasic 21-day pack, acute phase]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all tabs given in 1 pack; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all tabs given in 1 pack

[30 mcg EE monophasic 21-day pack, maintenance phase]: Dose: 1 tab PO qd x3wk, off 1wk; Info: may omit off wk for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack, acute phase]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs

[30 mcg EE monophasic 28-day pack, maintenance phase]: Dose: 1 tab PO qd; Info: may skip ferrous fumarate tabs for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack, acute phase]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs

[35 mcg EE monophasic 28-day pack, maintenance phase]: Dose: 1 tab PO qd; Info: may skip ferrous fumarate tabs for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

dysmenorrhea (off-label)

[20 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap)]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate caps for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

endometriosis (off-label)

[20 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap)]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate caps for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab)]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

renal dosing

[see below]: renal dz: not defined, caution advised

HD/PD: avoid use

hepatic dosing

[see below]: active hepatic dz: contraindicated

Peds Dosing .

Special Note

[20 mcg EE monophasic 21-day pack components]: Info: 21-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x21

[20 mcg EE monophasic 28-day pack (cap) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg cap x24, then ferrous fumarate 75 mg cap x4

[20 mcg EE monophasic 28-day pack (tab) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x21, then ferrous fumarate 75 mg tab x7; 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg tab x24, then ferrous fumarate 75 mg tab x4

[20 mcg EE monophasic 28-day pack (chewable tab) components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1 mg/20 mcg chewable tab x24, then ferrous fumarate 75 mg tab x4

[25 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 0.8 mg/25 mcg chewable tab x24, then ferrous fumarate 75 mg chewable tab x4

[30 mcg EE monophasic 21-day pack components]: Info: 21-day pack contains norethindrone/ethinyl estradiol 1.5 mg/30 mcg tab x21

[30 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 1.5 mg/30 mcg tab x21, then ferrous fumarate 75 mg tab x7

[35 mcg EE monophasic 28-day pack components]: Info: 28-day pack contains norethindrone/ethinyl estradiol 0.4 mg/35 mcg chewable tab x21, then ferrous fumarate 75 mg tab x7

[additional info]: Info: see Oral Contraceptive Pill (OCP) Hormonal Activity and Therapeutic Equivalence table

contraception

[20 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap), postmenarchal females]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

dysfunctional uterine bleeding, moderate (off-label)

[30 mcg EE monophasic 21-day pack, acute phase, postmenarchal females]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all tabs given in 1 pack; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all tabs given in 1 pack

[30 mcg EE monophasic 21-day pack, maintenance phase, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Info: may omit off wk for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack, acute phase, postmenarchal females]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs

[30 mcg EE monophasic 28-day pack, maintenance phase, postmenarchal females]: Dose: 1 tab PO qd; Info: may skip ferrous fumarate tabs for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack, acute phase, postmenarchal females]: Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all active tabs given in 1 pack, skip ferrous fumarate tabs

[35 mcg EE monophasic 28-day pack, maintenance phase, postmenarchal females]: Dose: 1 tab PO qd; Info: may skip ferrous fumarate tabs for extended or continuous cycle; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

dysmenorrhea (off-label)

[20 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap), postmenarchal females]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate caps for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

endometriosis (off-label)

[20 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (cap), postmenarchal females]: Dose: 1 cap PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate caps for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[20 mcg EE monophasic 28-day pack (chewable tab), postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[25 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 21-day pack, postmenarchal females]: Dose: 1 tab PO qd x3wk, off 1wk; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may omit off wk for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[30 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

[35 mcg EE monophasic 28-day pack, postmenarchal females]: Dose: 1 tab PO qd; Start: day 1 of menstrual cycle or 1st Sunday after onset of menses; Info: may skip ferrous fumarate tabs for extended or continuous cycle if pain persists; D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

renal dosing

[see below]: renal dz: not defined, caution advised

HD/PD: avoid use

hepatic dosing

[see below]: active hepatic dz: contraindicated

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Drugs

Classes

Drug Names

Select a medication above to begin.

norethindrone/ ethinyl estradiol

generic

Drug Monograph

Black Box Warnings .

Smoking and Cardiovascular Events

Adult Dosing .

Special Note

contraception

dysfunctional uterine bleeding, moderate (off-label)

dysmenorrhea (off-label)

endometriosis (off-label)

renal dosing

hepatic dosing

Peds Dosing .

Special Note

contraception

dysfunctional uterine bleeding, moderate (off-label)

dysmenorrhea (off-label)

endometriosis (off-label)

renal dosing

hepatic dosing