Symbicort

Adult Dosing .

Dosage forms:  MDI: 80 mcg/4.5 mcg per actuation, 160 mcg/4.5 mcg per actuation

COPD, maintenance tx

[2 puffs (160 mcg/4.5 mcg per actuation) inhaled bid]

Max: 640 mcg/18 mcg/day; Info: search 'gold' for epocrates COPD GOLD decision tools

asthma, maintenance tx

[2 puffs (80 mcg/4.5 mcg or 160 mcg/4.5 mcg per actuation) inhaled bid]

Start: varies by dz severity and current asthma tx, may incr. dose after 1-2wk; Max: 640 mcg/18 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

asthma, moderate-severe persistent (off-label)

[single-inhaler maintenance and reliever tx (SMART)]

Dose: 1-2 puffs inhaled qd-bid, then 1-2 puffs inhaled q4h prn; Start: varies by dz severity and current asthma tx; Max: 12 puffs/day; 54 mcg/day formoterol; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  MDI: 80 mcg/4.5 mcg per actuation, 160 mcg/4.5 mcg per actuation

asthma, maintenance tx

[6-11 yo]

Dose: 2 puffs (80 mcg/4.5 mcg per actuation) inhaled bid; Max: 320 mcg/18 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[12 yo and older]

Dose: 2 puffs (80 mcg/4.5 mcg or 160 mcg/4.5 mcg per actuation) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 1-2wk; Max: 640 mcg/18 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

asthma, moderate-severe persistent (off-label)

[single-inhaler maintenance and reliever tx (SMART), 5-11 yo]

Dose: 1-2 puff inhaled qd-bid, then 1-2 puffs inhaled q4h prn; Start: varies by dz severity and current asthma tx; Max: 8 puffs/day; 36 mcg/day formoterol; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[single-inhaler maintenance and reliever tx (SMART), 12 yo and older]

Dose: 1-2 puffs inhaled qd-bid, then 1-2 puffs inhaled q4h prn; Start: varies by dz severity and current asthma tx; Max: 12 puffs/day; 54 mcg/day formoterol; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised