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lisdexamfetamine
generic
Black Box Warnings .
Abuse, Misuse, and Addiction
CNS stimulants have high potential for abuse and misuse, can lead to substance use disorder, incl. addiction; misuse and abuse can result in overdose and death, risk incr. w/ higher doses or unapproved admin. methods; assess risk for abuse, misuse, and addiction before prescribing and throughout tx; educate pts and families about risks and proper drug storage and disposal; monitor frequently for s/sx of abuse, misuse, and addiction during tx
Adult Dosing .
Dosage forms: CAP: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg; CHEWABLE: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg
ADHD
- [30-70 mg PO qam]
- Start: 30 mg PO qam, may incr. by 10-20 mg/day qwk; Max: 70 mg/day; Info: duration 10-14h
binge eating disorder, moderate-severe
- [50-70 mg PO qam]
- Start: 30 mg PO qam, incr. by 20 mg/day qwk; Max: 70 mg/day
renal dosing
- [adjust dose amount]
- eGFR 15-29: max 50 mg/day; eGFR <15: max 30 mg/day
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: CAP: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg; CHEWABLE: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg
ADHD
- [6 yo and older]
- Dose: 30-70 mg PO qam; Start: 30 mg PO qam, may incr. by 10-20 mg/day qwk; Max: 70 mg/day; Info: duration 10-12h
renal dosing
- [adjust dose amount]
- eGFR 15-29: max 50 mg/day; eGFR <15: max 30 mg/day
- HD/PD: not defined
hepatic dosing
- [not defined]