cefuroxime axetil

Adult Dosing .

Dosage forms:  TAB: 250 mg, 500 mg

infections, mild-moderate bacterial

[250-500 mg PO bid x5-10 days]

Info: dose, duration varies w/ infection type, severity

pharyngitis/tonsillitis, streptococcal

[250 mg PO bid x10 days]

Info: not preferred per IDSA guidelines

sinusitis, acute maxillary

[250 mg PO bid x10 days]

Info: not recommended per IDSA guidelines

Lyme dz

[500 mg PO bid x14-21 days]

Info: for non-neurologic dz; give x14 days if early, localized dz; extend duration to 28 days if Lyme arthritis; 1st-line agent; search 'Lyme' for epocrates Lyme Disease Dx & Tx decision tool

pneumonia, community-acquired (off-label)

[500 mg PO bid for at least 5 days]

Info: part of multi-drug regimen; refer to IDSA guidelines

renal dosing

[adjust dose frequency]

CrCl 10-29: give usual dose q24h; CrCl <10: give usual dose q48h

HD: give usual dose q24h, on dialysis days admin. after dialysis; give usual dose as supplement after dialysis if next maint. dose not due right after dialysis; PD: give usual dose q24-48h; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  TAB: 250 mg, 500 mg

infections, mild-moderate bacterial

[<13 yo]

Dose: 250 mg PO bid x10 days

[13 yo and older]

Dose: 250-500 mg PO bid x5-10 days; Info: dose, duration varies by infection type, severity

otitis media, acute

[mild-moderate infection, 2-5 yo]

Dose: 250 mg PO bid x7 days

[mild-moderate infection, 6-12 yo]

Dose: 250 mg PO bid x5-7 days

[severe infection, 2-12 yo]

Dose: 250 mg PO bid x10 days

sinusitis, acute maxillary

[250 mg PO bid x10 days]

Info: not recommended per IDSA guidelines

pharyngitis/tonsillitis, streptococcal

[13 yo and older]

Dose: 250 mg PO bid x10 days; Info: not preferred per IDSA guidelines

Lyme dz

[13 yo and older]

Dose: 500 mg PO bid x14-21 days; Info: for non-neurologic dz; give x14 days if early, localized dz; extend duration to 28 days if Lyme arthritis; 1st-line agent; give susp w/ food; search 'Lyme' for epocrates Lyme Disease Dx & Tx decision tool

pneumonia, community-acquired (off-label)

[<13 yo]

Dose: 250 mg PO bid x10 days; Info: refer to IDSA guidelines

[13 yo and older]

Dose: 250-500 mg PO bid x10 days; Info: refer to IDSA guidelines

renal dosing

[adjust dose frequency]

CrCl 10-29: give usual dose q24h; CrCl <10: give usual dose q48h

HD: give usual dose q24h, on dialysis days admin. after dialysis; give usual dose as supplement after dialysis if next maint. dose not due right after dialysis; PD: give usual dose q24-48h; no supplement

hepatic dosing

[not defined]