megestrol

Adult Dosing .

Dosage forms:  TAB: 20 mg, 40 mg; SUSP: 40 mg per mL, 125 mg per mL

Special Note

[formulation clarification]

Info: 40 mg per mL susp and 125 mg per mL susp not bioequivalent or interchangeable

advanced breast CA, palliative tx

[40 mg PO qid]

Info: use tabs; consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

endometrial CA, palliative tx

[10-80 mg PO qid]

Info: use tabs; consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

anorexia or cachexia, AIDS-assoc.

[40 mg per mL susp]

Dose: 400-800 mg PO qd; Start: 800 mg PO qd; Info: consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

[125 mg per mL susp]

Dose: 625 mg PO qd; Info: consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

cachexia, cancer-related (off-label)

[40 mg per mL susp]

Dose: 400-800 mg PO qd; Start: 800 mg PO qd; Info: consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

[125 mg per mL susp]

Dose: 625 mg PO qd; Info: consider empiric glucocorticoid tx during stress/illness/surgery in pts on or being withdrawn from chronic tx

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  TAB: 20 mg, 40 mg; SUSP: 40 mg per mL, 125 mg per mL

Special Note

[formulation clarification]

Info: 40 mg per mL susp and 125 mg per mL susp not bioequivalent or interchangeable

cachexia, chronic dz-related (off-label)

[6 mo and older]

Dose: 7.5-10 mg/kg/day PO divided qd-bid; Max: 800 mg/day

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]