dexlansoprazole

Adult Dosing .

Dosage forms:  DR CAP: 30 mg, 60 mg

GERD, non-erosive symptomatic

[30 mg PO/NG qd x4wk]

Info: may open cap, see PPI Administration Alternatives table

erosive esophagitis

[initial tx]

Dose: 60 mg PO/NG qd for up to 8wk; Info: may open cap, see PPI Administration Alternatives table

[maintenance tx]

Dose: 30 mg PO/NG qd; Info: may open cap, see PPI Administration Alternatives table

H. pylori infection (off-label)

[30-60 mg PO bid x14 days]

Info: part of multi-drug regimen, dosing may vary; may open cap, see PPI Administration Alternatives table; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[erosive esophagitis initial tx]

Child-Pugh Class B: 30 mg qd; Child-Pugh Class C: avoid use

[all other indications]

Child-Pugh Class C: avoid use

Peds Dosing .

Dosage forms:  DR CAP: 30 mg, 60 mg

GERD, non-erosive symptomatic

[12 yo and older]

Dose: 30 mg PO/NG qd x4wk; Info: may open cap, see PPI Administration Alternatives table

erosive esophagitis

[initial tx, 12 yo and older]

Dose: 60 mg PO/NG qd for up to 8wk; Info: may open cap, see PPI Administration Alternatives table

[maintenance tx, 12 yo and older]

Dose: 30 mg PO/NG qd; Info: may open cap, see PPI Administration Alternatives table

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[erosive esophagitis initial tx]

Child-Pugh Class B: 30 mg qd; Child-Pugh Class C: avoid use

[all other indications]

Child-Pugh Class C: avoid use