Synarel

Adult Dosing .

Dosage forms:  SPRAY: 200 mcg per actuation

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing

endometriosis

[1 actuation in one nostril bid x6mo]

Start: day 2-4 of menstrual cycle; Info: may incr. to 1 actuation in each nostril bid if inadequate response after 2mo

premature ovulation prevention (off-label)

[individualize dose intranasally bid-tid]

Info: for inhibition of premature LH surge during controlled ovarian stimulation w/ ART; refer to institution protocols for dose and duration

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  SPRAY: 200 mcg per actuation

central precocious puberty

[2 actuations in each nostril bid]

Info: cont. tx until resumption of puberty desired; may incr. to 3 actuations in one nostril tid if inadequate response

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]