Celestone Soluspan

Adult Dosing .

Dosage forms:  INJ (50%/50%): 6 mg per mL

corticosteroid-responsive conditions

[intramuscular route]

Dose: 0.25-9 mg IM qd; Info: dose, frequency varies by condition; taper to maint. dose after adequate response; taper dose gradually to D/C if high-dose or long-term use

[intra-articular route]

Dose: 1.5-3 mg INJ for smaller joints, 6-12 mg INJ for larger joints; Info: dose, frequency varies by condition and injection site; taper to maint. dose after adequate response; taper dose gradually to D/C if high-dose or long-term use

[intra-lesional/soft tissue injection]

Dose: 1.5-6 mg INJ q3-14 days; Info: dose, frequency varies by condition and injection site; taper to maint. dose after adequate response; taper dose gradually to D/C if high-dose or long-term use

multiple sclerosis, acute exacerbation

[30 mg IM qd x7 days, then 12 mg IM qod x1mo]

Info: taper dose gradually to D/C

fetal lung maturation (off-label)

[12 mg IM q24h x2 doses]

Info: for expectant mothers 24 wk,0 days-33 wk,6 days gestation at high risk of preterm delivery; may consider for mothers at least 23 wk,0 days gestation at high risk of preterm delivery w/in 7 days; may repeat x1 for mothers <34wk,0 days gestation at imminent risk of preterm birth w/in 7 days and no prior antenatal steroid use w/in 14 days; may consider for mothers at least 34 wk,0 days-36wk,6 days gestation at imminent risk of preterm birth w/in 7 days and no prior antenatal steroid use

renal dosing

[see below]

renal impairment: no adjustment

HD: not defined; PD: no adjustment; supplement not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (50%/50%): 6 mg per mL

corticosteroid-responsive conditions

[0.02-0.3 mg/kg/day IM divided tid-qid]

Alt: 0.6-9 mg/m^2/day IM divided tid-qid; Info: dose, frequency varies by condition; taper to maint. dose after adequate response; taper dose gradually to D/C if high-dose or long-term use

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

hepatic dosing

[not defined]