cefadroxil

Adult Dosing .

Dosage forms:  CAP: 500 mg; TAB: 1000 mg; SUSP: 250 mg per 5 mL, 500 mg per 5 mL

infections, bacterial

[1-2 g/day PO divided q12-24h]

Info: dose, duration varies w/ infection type, severity

pharyngitis/tonsillitis, streptococcal

[1 g/day PO divided q12-24h x10 days]

UTI, uncomplicated

[1-2 g/day PO divided q12-24h x3-7 days]

Info: not 1st-line agent

skin/skin structure infections, bacterial

[1 g/day PO divided q12-24h x5-7 days]

Info: may extend duration based on clinical response

renal dosing

[adjust dose amount, frequency]

CrCl 25-50: 1 g x1, then 500 mg q12h; CrCl 10-25: 1 g x1, then 500 mg q24h; CrCl <10: 1 g x1, then 500 mg q36h

HD: 1 g q72h, on dialysis days admin. after dialysis; consider 1 g supplement if next maint. dose not due right after dialysis; PD: 500 mg q24h; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  CAP: 500 mg; TAB: 1000 mg; SUSP: 250 mg per 5 mL, 500 mg per 5 mL

infections, bacterial

[30 mg/kg/day PO divided q12-24h]

Max: 2 g/day; Info: dose, duration varies w/ infection type, severity

pharyngitis/tonsillitis, streptococcal

[30 mg/kg/day PO divided q12-24h x10 days]

Max: 2 g/day

UTI, uncomplicated

[30 mg/kg/day PO divided q12h x7-10 days]

Max: 2 g/day

skin/skin structure infections, bacterial

[30 mg/kg/day PO divided q12-24h x5-7 days]

Max: 2 g/day; Info: may extend duration based on clinical response

renal dosing

[adjust dose frequency]

CrCl 11-34: give 50% usual divided dose q12h; CrCl <11: give 50% usual divided dose q18-24h

HD: 25 mg/kg/dose q24h, on dialysis days admin. after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: 25 mg/kg/dose q24h; no supplement

hepatic dosing

[not defined]