Select a medication above to begin.
Exforge HCT
amlodipine/ valsartan/ hydrochlorothiazide
Black Box Warnings .
Fetal Toxicity
fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected
Adult Dosing .
Dosage forms: TAB: 5 mg/160 mg/12.5 mg, 5 mg/160 mg/25 mg, 10 mg/160 mg/12.5 mg, 10 mg/160 mg/25 mg, 10 mg/320 mg/25 mg
HTN
- [1 tab PO qd]
- Start: same dose of each component if replacement tx or start combo at lower dose of any component if add-on tx; may incr. dose after 2wk; Max: 10 mg/320 mg/25 mg/day; Info: not for initial tx
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl 10-30: not defined, caution advised; CrCl <10: avoid use; anuria: contraindicated
- HD/PD: avoid use
hepatic dosing
- [see below]
- hepatic impairment: consider starting 5 mg/160 mg/12.5 mg or 5 mg/160 mg/25 mg qd
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.