Hiberix

Adult Dosing .

Dosage forms:  INJ

invasive Haemophilus influenzae type b dz prevention (off-label)

[pts w/ asplenia or sickle cell dz]

Dose: 0.5 mL IM x1; Info: for previously unvaccinated pts; give at least 2wk prior to elective splenectomy; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[pts w/ HSCT]

Dose: 0.5 mL IM x3 doses 4wk apart; Start: 6-12mo after successful hematopoietic stem cell transplant; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

invasive Haemophilus influenzae type b dz prevention

[6 wk old-6 mo at series start]

Dose: 0.5 mL IM x1 at 2 mo, 4 mo, 6 mo, and 12-15 mo for 4 total doses; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[7-11 mo at series start]

Dose: 0.5 mL IM x2 doses at least 4wk apart, then 0.5 mL IM x1 at least 8wk later or at 12-15 mo; Info: may give 3rd dose 8wk after 2nd dose if 1st dose given before 12 mo and 2nd dose given before 15 mo; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[12-14 mo at series start]

Dose: 0.5 mL IM x2 doses at least 8wk apart; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[15-59 mo at series start]

Dose: 0.5 mL IM x1; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[special situations, 12 mo and older (off-label)]

Dose: varies by situation; Info: for pts w/ asplenia, sickle cell dz, elective splenectomy, HIV infection, or immunocompromise; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]